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Organic Chemistry

IIT-JAM Chemistry — Natural Products previous year questions

19 questions · 2005 · all with verified answer · last checked 2026-11-10

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Q1 · 2005-2022 · 2 marks

Match the isoelectric point with the amino acids. Amino acids Isoelectric point (X) \mathrm{H_2NCH_2COOH} (I) 9.5 (Y) \mathrm{HOOCCH_2CH_2CH(NH_2)COOH} (II) 6.0 (Z) \mathrm{H_2N(CH_2)_4CH(NH_2)COOH} (III) 3.1
  • (a) (X)-(II), (Y)-(III), (Z)-(I)
  • (b) (X)-(III), (Y)-(I), (Z)-(II)
  • (c) (X)-(I), (Y)-(II), (Z)-(III)
  • (d) (X)-(II), (Y)-(I), (Z)-(III) IIT JAM 2006
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Answer: (a)

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Q2 · 2005-2022 · 2 marks

The complementary strand of DNA for the following single stranded DNA sequence, 5′–A–T–C–A–T–G–C–3′ is
  • (a) 5′–A–T–C–A–T–G–C–3′
  • (b) 5′–T–A–G–T–A–C–G–3′
  • (c) 5′–G–C–A–T–G–A–T–3′
  • (d) 5′–C–G–T–A–C–T–A–3′
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Answer: (c)

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Q3 · 2005-2022 · 2 marks

The structure of D-galactose is Structure for this questionWhich one of these structures is L-galactose?
  • (a) Structure for this question
  • (b) Structure for this question
  • (c) Structure for this question
  • (d) Structure for this question
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Answer: (d)

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Q4 · 2005-2022 · 2 marks

Calculate the isoelectric point (p.I.) of lysine, given the \mathrm{p}K_a of \alpha.\mathrm{NH_3} is 8.95, \mathrm{p}K_a of side chain \mathrm{NH_3} is 10.53 and \mathrm{p}K_a of \alpha.COOH is 2.18.
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Answer: 9.74

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Q5 · 2005-2022 · 2 marks

The absolute configurations at the two chiral centers in D-Ribulose are D-Ribulose
  • (a) 3R, 4R
  • (b) 3 \mathrm{R}, 4 \mathrm{~S}
  • (c) Structure for this question3 \mathrm{~S}, 4 \mathrm{R}
  • (d) 3 \mathrm{~S}, 4 \mathrm{~S}
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Answer: (a)

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Q6 · 2005-2022 · 2 marks

The correct relationship within each pair of the natural products is:
  • (a) Camphor - terpene; insulin - protein; nicotine - alkaloids; streptomycin - carbohydrate
  • (b) Camphor - terpene; insulin - carbohydrate; nicotine - alkaloid; streptomycin - lipid
  • (c) Camphor-alkaloid; insulin-protein; nicotine-terpene; streptomycin-carbohydrate.
  • (d) Camphor - carbohydrate; insulin - protein; nicotine - alkaloid; streptomycin - terpene.
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Answer: (a)

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Q7 · 2005-2022 · 2 marks

The Haworth projection for \alpha-anomer of D-glucose is
  • (a) Structure for this question
  • (b) Structure for this question
  • (c) Structure for this question
  • (d) Structure for this question
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Answer: (c)

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Q8 · 2005-2022 · 2 marks

The complementary DNA sequence of the given DNA 5'-G-A-A-T-T-C-3' is:
  • (a) 5'-C-T-T-A-A-G-3'
  • (b) 5'-C-U-U-A-A-G-3'
  • (c) 3'-C-T-T-A-A-G-5'
  • (d) 3'-G-A-A-T-T-C-5'
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Answer: (c)

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Q9 · 2005-2022 · 2 marks

\alpha-Farnesene shown below is a
  • (a) Structure for this questionditerpene having two isoprene units
  • (b) triterpene having three isoprene units
  • (c) triterpene having four isoprene units
  • (d) Sesquiterpene having three isoprene units.
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Answer: (d)

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Q10 · 2005-2022 · 2 marks

Which one of the following statements is Correct?
  • (a) Naturally occuring DNA has \beta-configuration.
  • (b) Nucleic acids are derived from proteins.
  • (c) Proteins store genetic information
  • (d) Vitamins generally act as enzymes IIT JAM 2014
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Answer: (a)

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Q11 · 2005-2022 · 2 marks

Tollen's test will be negative for: Structure for this questionStructure for this questionStructure for this questionStructure for this question
  • (a) Glucose
  • (b) Mannose
  • (c) Sucrose
  • (d) Galactose
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Answer: (c)

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Q12 · 2005-2022 · 2 marks

The \mathrm{pK_a} values of lysine are 2.18, 8.95 and 10.79. The isoelectric point of lysine is ____ IIT JAM 2016
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Answer: 9.87

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Q13 · 2005-2022 · 2 marks

The most basic amino acid among the following is
  • (a) tyrosine
  • (b) methionine
  • (c) arginine
  • (d) glutamine
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Answer: (c)

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Q14 · 2005-2022 · 2 marks

The maximum number of dipeptides that could be obtained by reaction of phenylalanine with leucine is ____
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Answer: 2

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Q16 · 2005-2022 · 2 marks

The C-2 epimer of D-glucose is
  • (a) D-Mannose
  • (b) D-Fructose
  • (c) D-Galactose
  • (d) D-Gulose
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Answer: (a)

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Q17 · 2005-2022 · 2 marks

Based on the information given below, the isoelectric point (pI) of lysine is ____ (Round off to one decimal place) Structure for this questionStructure for this questionStructure for this questionStructure for this questionStructure for this questionStructure for this questionStructure for this questionIIT JAM 2020
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Answer: 9.8

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Q19 · 2005-2022 · 2 marks

The nucleobase NOT found DNA is
  • (a) Thymine
  • (b) Uracil
  • (c) Guanine
  • (d) Adenine
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Answer: (b)

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